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KMID : 0388220130200060369
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Journal of the Korean Rheumatism Association
2013 Volume.20 No. 6 p.369 ~ p.373
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A Case of Behcet’s Disease Associated with Schizophrenia and Myelodysplastic Syndrome with Trisomy 8 and 9
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Baek Jung-Hun
Chun Hyun-Jung
Park Youn-Hee
Cho Jeong-Hyeon
Bae Sang-Kyun
Ha You-Jung
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Abstract
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Behcet’s disease (BD) is a multi-systemic inflammatory disease of unknown origin that affects nearly all organs. Recent reports of BD with myelodysplastic syndrome (MDS) often note an association with gastrointestinal involvement and trisomy 8. We herein report on a case of a 51-year-old man who had refractory schizophrenia and developed gastrointestinal BD and MDS with trisomy 8 and 9. He visited our hospital due to fever and abdominal pain. Multiple ulcerations in the colorectum were observed on colonoscopy, and he was diagnosed with intestinal BD. During the treatment of intestinal BD, anemia and thrombocytopenia developed. His bone marrow study revealed myelodysplastic syndrome (refractory anemia with ringed sideroblast) with trisomy 8 and trisomy 9. We report a rare case of intestinal BD accompanied by schizophrenia and myelodysplastic syndrome with trisomy 8 and 9.
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KEYWORD
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Behcet’s disease , Myelodysplastic syndrome , Schizophrenia
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